MATING TYPE AND SPORULATION IN YEAST I. MUTATIONS WHICH ALTER MATING-TYPE CONTROL OVER SPORULATION

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Mating type and sporulation in yeast. I. Mutations which alter mating-type control over sporulation.

In Saccharomyces cerevisiae, meiosis and spore formation as well as mating are controlled by mating-type genes. Diploids heterozygous for mating type (aalpha) can sporulate but cannot mate; homozygous aa and alpha-alpha diploids can mate, but cannot sporulate. From an alpha-alpha diploid parental strain, we have isolated mutants which have gained the ability to sporulate. Those mutants which co...

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Mating Type and Sporulation in Yeast. 11. Meiosis, Recombination, and Radiation Sensitivity in an (yly Diploid with Altered Sporulation Control

In wild-type S. cerevisiae, diploid cells must be heterozygous at the matingtype locus in order to sporulate. In the preceding paper, we described a number of mutants (CSP mutants), isolated from nonsporulating aa and aa parent strains, in which sporulation appeared to be uncoupled from control by mating type. The characterization of one of these mutants (CSPI) is now extended to other processe...

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Given a nutritional regime marked by a low nitrogen level and the absence of fermentable carbon sources, conventional a/alpha diploid cells of Saccharomyces cerevisiae exhibit a complex developmental sequence that includes a round of premeiotic DNA replication, commitment to meiosis and the elaboration of mature tetrads containing viable ascospores. Ordinarily, haploid cells and diploid cells o...

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Yeast Mating Type

Saccharomyces cerevisiae, baker’s yeast, can exist in either a haploid (1n) or a diploid (2n) state. Haploids express one of two mating types, a or a (alpha). Haploids of either mating type are capable of mating with haploids of the opposite mating type in response to the action of mating pheromones. Mating results in fusion of haploid cells, forming an a/a diploid, which is no longer capable o...

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ژورنال

عنوان ژورنال: Genetics

سال: 1975

ISSN: 1943-2631

DOI: 10.1093/genetics/80.1.41